CUSTOM ORGANIC SYNTHESIS & CDMO

Contract Synthesis & Full-Time Equivalent (FTE) Services

Synthesis of complex organic molecules is our core competence. Leveraging decades of chemical research experience and agile laboratory management, we turn around challenging synthetic targets with guaranteed purity and complete IP protection.

Pharmavive Synthesis Facility
Custom Organic Synthesis & Kilo Scale-Up Lab
Gram to Multi-Kilogram Capacity

Synthetic Innovation for Every Stage of Drug Development

Our synthetic operations bridge laboratory discovery with kilo scale-up. Equipped with VAV fume hoods, automated hydrogenation, cryogenic reactors, and rotary evaporators, we handle complex multi-step transformations under rigorous safety protocols.

Whether you require a single milligram batch of a toxic degradation impurity or multi-kilogram intermediate manufacturing, our team delivers reproducible chemical excellence.

Milligram to Kilogram ScaleStereoselective SynthesisCryogenic Reactions (-78°C)High-Pressure Hydrogenation
Chemical Services

Custom Synthesis Capabilities

01

Custom Synthesis of Complex Organic Molecules

Multi-step synthetic routes, heterocyclic chemistry, macrocycles, and stereoselective organic transformations.

02

Pharmaceutical Reference Standards

High-purity primary and secondary reference standards for impurity identification and assay qualification.

03

Stable Isotope Labelled Compounds (SIL)

Deuterium (D), Carbon-13 (13C), and Nitrogen-15 (15N) labeled compounds for quantitative bioanalytical LC-MS/MS.

04

Drug Metabolites & Glucuronides

Phase I and Phase II metabolites, glucuronide conjugates, sulfates, and N-oxides for preclinical DMPK studies.

05

Isolation & Unknown Impurity Elucidation

Semi-preparative HPLC isolation from stressed API batches followed by comprehensive spectroscopic structure identification.

06

Genotoxic & Nitrosamine Impurities

Targeted synthesis of trace-level mutagenic impurities with rigorous analytical safety handling and packaging.

07

Process Scale-Up & Kilo Lab Manufacturing

Scale-up from milligram feasibility to multi-kilogram non-GMP / regulatory starting material batches.

08

Peptide Synthesis & Coupling Reagents

Solid-phase and solution-phase peptide synthesis, specialized amino acid derivatives, and high-efficiency coupling reagents.

DEDICATED RESEARCH TEAMS

Full-Time Equivalent (FTE) Collaboration

For complex, longer-term, or iterative medicinal chemistry programs, our FTE model provides a dedicated team of Ph.D. scientists operating as a seamless extension of your internal laboratory.

Predictable Cost & Scalability

A flat, transparent monthly rate per scientist that eliminates administrative overhead and enables agile task pivoting without rewriting work orders.

Direct Project Management

Regular bi-weekly video conferences, comprehensive written milestone reports, and real-time electronic laboratory notebook (ELN) synchronization.

Complete Analytical Access

FTE teams have immediate, unhindered access to our LCMS, HPLC, GC-HS, and NMR suites, ensuring rapid reaction monitoring and zero analytical bottlenecks.

Project Workflow

From Inquiry to Compound Delivery

01

Inquiry & Requirements

Send project structures, CAS numbers, or synthetic target specifications to [email protected] or via our RFQ form.

02

Feasibility & Route Scouting

Our synthetic chemistry team conducts literature review, retro-synthetic analysis, and provides a formal proposal with lead time.

03

Synthesis & Optimization

Under dedicated Ph.D. chemist supervision, synthesis proceeds with bi-weekly updates, milestone reports, and real-time communication.

04

Analytical Quality Release

Batches undergo comprehensive testing (1H/13C-NMR, LC-MS, HPLC Purity, TGA) to ensure strict compliance.

05

Secure Delivery & CoA

Door-to-door temperature-controlled delivery worldwide, accompanied by complete analytical dossiers and safety data sheets.

Code of Conduct & IP Protection

Contractually guaranteed measures safeguarding your chemical discoveries

100% Client IP OwnershipAll synthetic routes, compound samples, analytical data, and intellectual property generated belong exclusively to the client.
Zero Conflict of InterestWe do not accept overlapping or competing research projects that could create conflicts with client programs.
Strict ConfidentialityComprehensive NDAs cover all personnel, physical premises, and electronic communications with encrypted archiving.